A Longitudinal Study of Neuromyelitis Optica and Transverse Myelitis
Principal Investigator: Benjamin Greenberg, MD, MHS
Study Site: University of Texas Southwestern & Children’s Medical Center, Dallas, TX
Clinical Trials.Gov Identifier: NCT01623076
This observational study seeks to determine the biologic causes of inflammation in patients with Neuromyelitis Optica (NMO), Neuromyelitis Optica Spectrum Disorder, Transverse Myelitis and Optic Neuritis. While patients will be treated according to decisions with their treating physician, this study will collect data and samples from patients prospectively to gain a better understanding of the disease. The study is seeking to understand why some patients respond to medications, while others do not; and what happens biologically, preceding relapses. Gathering these data and samples will allow researchers to identify new ways of diagnosing and treating these diseases. Data and samples will be shared with researchers around the world to support collaborative efforts to treat these conditions.
Patients previously diagnosed with Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder, Transverse Myelitis and Optic Neuritis and healthy controls will be eligible to participate in this study. Males and females six years and older, who are either able to consent for themselves or where the parent is able to give informed consent, and who are able to maintain scheduled visits to University of Texas Southwestern Medical Center will be recruited in this study. Patients will donate serum, plasma, DNA, RNA and white blood cells. There is no monetary compensation. There is no cost to you. You will not receive any personal health benefits as a result of your participation in this observational research study. We hope that the results will help us better identify new ways of diagnosing and treating these disorders. Your participation is voluntary.
If you are interested in participating, please contact the University of Texas Southwestern Medical Center at the contacts below.