The primary objective of this study is to determine how well specific neuroimaging modalities detect the different aspects of anomalous white matter development associated with pediatric NMOSD. Our purpose is to acquire data using neuroimaging obtained at 3.0 Tesla as well as neurobehavioral data to better characterize neuroimaging features and function in this rare population.
This study takes part in two phases. For the first part, participants will undergo neuropsychological (cognitive) testing and have a “mock” or practice magnetic resonance imaging (MRI) scan”. The purpose of this “mock” scan is to improve comfort, decrease potential anxiety, and to train you to lie still while in the scanner. After the “mock”/practice scan, participants will have the MRI exam. The MRI scan could take up to 1 hour. Participants are in this study for one day for approximately 3-4 hours.